MONTAKAST-L

Montelukast  
Levocetirizine

Montakast-L Tablet is a combination medicine used in the treatment of allergic symptoms such as runny nose, stuffy nose, sneezing, itching, swelling, watery eyes and congestion or stuffiness. It also reduces inflammation in the airways and make breathing easier.

 

Introduction

Montakast-L Tablet is a combination medicine used in the treatment of allergic symptoms such as runny nose, stuffy nose, sneezing, itching, swelling, watery eyes and congestion or stuffiness. It also reduces inflammation in the airways and make breathing easier.


Montakast-L Tablet is taken with or without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.


The most common side effects are nausea, diarrhoea, vomiting, dryness in the mouth, headache, skin rash, flu-like symptoms, and fatigue. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine may cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness.


Never support self-medication or recommend your medicine to another person. It is beneficial to have plenty of fluids while taking this medication. Before you start taking this medicine it is important to inform your doctor if you are suffering from kidney disease.

 

MECHANISM

HOW MONTAKAST-L TABLET WORKS

Montakast-L Tablet is a combination of two medicines: Levocetirizine and Montelukast, which relieves sneezing and runny nose due to allergies. Levocetirizine is an antiallergic which blocks a chemical messenger (histamine) responsible for runny nose, watery eyes and sneezing. Montelukast is a leukotriene antagonist. It works by blocking another chemical messenger (leukotriene). This reduces inflammation (swelling) in the airways and nose, and improves symptoms.


Montelukast is a Leukotriene receptor antagonists.(is used for maintenance treatment of asthma and to relive symptoms of seasonal allergies) It is a selective and orally active leukotriene antagonist that inhibits the cysteinyl leukotriene CysLT1 receptor. 


Levocetirizine is a third — generation non — sedative antihistamine.(is prevents the release of other allergy chemicals and increased blood supply to the area, and provides relief from the typical symptoms of hay fever). Levocetirizine, the R — entaiomer of Cetirizine, is a potent and selective antagonist of peripheral H1 — receptors. 


It has been demonstrated by recent studies concomitant administration of an antileukotriene (montelukast) and an antihistamine (levocetirizine), shows significantly better symptoms relief compared with the modest improvement of rhinitis symptomatology with each of the treatments alone. 


Montelukast: Add — on therapy for the treatment of patients, 6 years old or older, with mild to moderate asthma in adequately controlled on 'as required' short — acting β — agonist and inhaled corticosteroids. Montelukast may offer an alternative to Theophylline as add — on therapy is asthma poorly controlled by short acting β — agonist and inhaled corticosteroids. 


Levocetirizine: skin allergy like food and drug allergy or atopic dermatitis, chronic idiopathic urticaria

 

INDICATIONS AND USAGE:

  • Allergy Control

  • Sneezing and runny nose due to allergies

  • Hay fever

  • Allergic skin conditions

  • Prophylactic treatment of asthma.

  • Chronic treatment of asthma associated with allergy.

  • Seasonal and perennial rhinitis.

 

DRUG INTERACTION:


BEFORE TAKING THIS MEDICINE TELL THE DOCTOR ABOUT ANY MEDICAL PROBLEMS AN ALLERGIES THAT CHILD HAS NOW OR HAS HAD.


Some medicines may affect how patient's works, or other medicine work. If anyone is taking or has recently taken other medicines, including those obtained without a prescription.
Such as: 

  • Phenobarbital: Used for treatment of epilepsy 

  • Phenytoin: Used for treatment of epilepsy 

  • Rifampicin: Used for treatment of Tuberculosis and some other interactions. 

  • Theophylline, Predisolone, Oral Contraceptives, Terfenadine, Digoxin, Warafin, Thyroid Hormones & Sedative Hypnotics.

ADVERSE EFFECTS:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

  • Diarrhea

  • Dryness in mouth

  • Fatigue

  • Headache

  • Nausea

  • Skin rash

  • Sleepiness

  • Vomiting